Traditional Herbs Database

Anxiety relief, sleep aid, muscle relaxation

Valerenic acid, isovaleric acid, GABA modulators, flavonoids

Enhances GABA neurotransmission, similar to benzodiazepines but through different binding sites

Anxiety relief, stress reduction, mild euphoria

Kavalactones (kavain, dihydrokavain, methysticin)

Modulates GABA-A receptors and inhibits monoamine oxidase B

Mild anxiety, insomnia, restlessness, nervous tension

Flavonoids, alkaloids, phenolic compounds, maltol

Increases GABA levels in the brain, mild MAO inhibition

Anxiety, stress, insomnia, cognitive function

Rosmarinic acid, citral, citronellal, flavonoids

Inhibits GABA transaminase increasing GABA levels, moderate cholinergic receptor activity

Anxiety, insomnia, nerve pain, mild depression

Isoquinoline alkaloids (protopine, allocryptopine), flavonoids

Binds to benzodiazepine receptors but with lower affinity, modulates dopamine metabolism

Anxiety, insomnia, muscle tension, nervous exhaustion, seizures

Scutellarin, baicalin, wogonin, flavonoids

GABA modulation, mild sedative effects, reduces muscle spasms

Anxiety, insomnia, digestive calming, mild inflammation, skin conditions

Apigenin, bisabolol, chamazulene, flavonoids

Binds to benzodiazepine receptors, anti-inflammatory, antispasmodic

Anxiety, insomnia, restlessness, digestive issues, headache

Linalool, linalyl acetate, borneol, terpenes

Modulates GABA transmission, serotonergic effects, reduces sympathetic nervous system activity

Mild to moderate depression, anxiety, seasonal affective disorder

Hypericin, hyperforin, flavonoids, xanthones

Inhibits reuptake of serotonin, dopamine, and norepinephrine; modulates GABA receptors

Depression, anxiety, PMS symptoms, sexual dysfunction

Crocin, crocetin, safranal, picrocrocin

Inhibits reuptake of dopamine, norepinephrine, and serotonin; NMDA receptor modulation

Depression, fatigue, stress, cognitive function, physical performance

Rosavins, salidroside, tyrosol, rhodioflavonoside

Modulates HPA axis, increases serotonin, norepinephrine, and dopamine levels in the brain

Depression, osteoarthritis, liver health

S-adenosyl-L-methionine (endogenous compound)

Increases synthesis of neurotransmitters, improves receptor function, enhances methylation

Depression, anxiety, insomnia, fibromyalgia, weight management

5-hydroxytryptophan (from Griffonia simplicifolia seeds)

Direct precursor to serotonin, crosses blood-brain barrier

Inflammation, joint pain, cognitive function, digestive support

Curcumin, demethoxycurcumin, bisdemethoxycurcumin, volatile oils

Inhibits NF-κB, COX-2, and pro-inflammatory cytokines; antioxidant activity

Osteoarthritis, rheumatoid arthritis, inflammatory bowel disease, asthma

Boswellic acids (AKBA, KBA), triterpenes

Inhibits 5-lipoxygenase (5-LOX), reduces leukotriene synthesis, inhibits NF-κB

Inflammation, joint pain, nausea, digestive health, circulation

Gingerols, shogaols, paradols, zingerone

Inhibits COX-2, lipoxygenase, and pro-inflammatory cytokines; antioxidant activity

Osteoarthritis, back pain, tendonitis, digestive disorders

Iridoid glycosides (harpagoside, harpagide), procumbide

Inhibits COX-2, reduces inflammatory mediators, modulates cytokine production

Pain relief, fever reduction, headaches, back pain, osteoarthritis

Salicin, salicylic acid, flavonoids, tannins

Metabolized to salicylic acid; inhibits prostaglandin synthesis

Stress reduction, anxiety, cognitive function, thyroid support

Withanolides, alkaloids, saponins, iron

Modulates cortisol levels, GABA receptors, and inflammatory pathways

Energy, cognitive function, immune support, stress resistance, sexual function

Ginsenosides, panaxosides, polysaccharides, flavonoids

Modulates HPA axis, increases NO production, antioxidant activity, neuroprotection

Stress resistance, energy, immune support, athletic performance, cognitive function

Eleutherosides, glycosides, polysaccharides, flavonoids

Modulates HPA axis, enhances stress resistance, improves oxygen utilization

Stress reduction, cognitive function, blood sugar balance, immune support

Eugenol, rosmarinic acid, ursolic acid, caryophyllene

Corticosteroid modulation, antioxidant effects, neuroprotection, anti-inflammatory

Stress protection, liver health, cognitive function, physical endurance, adrenal support

Schisandrins, lignans, essential oils, vitamins

Antioxidant effects, hepatoprotective, increases stress resilience, enhances mitochondrial function

Stress resistance, energy, immune support, athletic performance, cognitive function

Eleutherosides, glycosides, polysaccharides, flavonoids

Modulates HPA axis, enhances stress resistance, improves oxygen utilization

Stress protection, liver health, cognitive function, physical endurance, adrenal support

Schisandrins, lignans, essential oils, vitamins

Antioxidant effects, hepatoprotective, increases stress resilience, enhances mitochondrial function

Stress reduction, cognitive function, blood sugar balance, immune support

Eugenol, rosmarinic acid, ursolic acid, caryophyllene

Corticosteroid modulation, antioxidant effects, neuroprotection, anti-inflammatory

Energy, endurance, oxygen utilization, immune support, kidney function

Cordycepin, adenosine, polysaccharides, sterols

Increases ATP production, improves oxygen utilization, enhances cellular immunity

Liver protection, detoxification support, antioxidant

Silymarin (mixture of flavonolignans), silibinin, silychristin, silydianin

Stabilizes cell membranes, promotes glutathione production, antioxidant activity

Liver cleansing, bile production, digestive support, gentle detoxification

Taraxacin, taraxasterol, inulin, flavonoids, minerals

Stimulates bile flow, supports hepatic detoxification pathways, antioxidant activity

Liver function, bile flow, cholesterol reduction, digestion

Cynarin, luteolin, chlorogenic acid, flavonoids

Stimulates bile production, antioxidant activity, lipid metabolism modulation

Liver support, blood purification, skin conditions, digestive health

Arctiin, arctigenin, inulin, polyphenols, flavonoids

Antioxidant activity, promotes bile secretion, blood purification

Liver support, iron absorption, skin conditions, mild laxative

Anthraquinones, flavonoids, tannins, iron, vitamins

Mild choleretic effect, antioxidant activity, iron metabolism support

Nausea, indigestion, gas, morning sickness, motion sickness, inflammation

Gingerols, shogaols, zingerone, volatile oils

Increases gastric motility, stimulates saliva and gastric secretions, anti-inflammatory

Bloating, gas, colic, indigestion, IBS symptoms, mild spasms

Anethole, fenchone, estragole, volatile oils

Antispasmodic effects on smooth muscle, carminative, mild estrogenic activity

IBS, dyspepsia, intestinal cramps, bloating, nausea, gallstones

Menthol, menthone, limonene, cineole, flavonoids

Calcium channel modulation in intestinal smooth muscle, carminative, choleretic effects

Immune support, upper respiratory infections, cold and flu symptoms

Alkamides, polysaccharides, caffeic acid derivatives, echinacoside

Activates macrophages, NK cells, increases phagocytosis, modulates cytokine production

Immune support, fatigue, stress, heart health, diabetes support

Astragalosides, polysaccharides, flavonoids, amino acids

Enhances NK cell activity, increases T-cell proliferation, modulates Th1/Th2 balance

Immune modulation, cancer support, antioxidant, stress, sleep, liver support

Beta-glucans, triterpenes, polysaccharides, sterols, ganoderic acids

Enhances macrophage and NK cell activity, modulates cytokine production, adaptogenic effects

Bacterial and fungal infections, respiratory infections, digestive issues

Carvacrol, thymol, terpenes, phenols

Disrupts cell membrane integrity of pathogens, inhibits microbial growth

Respiratory infections, cough, bronchitis, fungal infections, GI infections

Thymol, carvacrol, rosmarinic acid, flavonoids

Disrupts microbial cell membranes, bronchodilatory effects, anti-inflammatory

Antimicrobial, cardiovascular health, immune support, cholesterol management

Allicin, ajoene, diallyl disulfide, S-allyl cysteine

Inhibits bacterial, viral, and fungal growth; enhances immune cell activity; reduces cholesterol synthesis

Immune support, upper respiratory infections, wound healing, antiviral

Alkamides, polysaccharides, chicoric acid, flavonoids

Increases white blood cell activity, enhances phagocytosis, modulates cytokine production

Bacterial and fungal infections, digestive infections, mucous membrane inflammation

Berberine, hydrastine, canadine, alkaloids

Inhibits bacterial adhesion, disrupts biofilm formation, anti-inflammatory effects

Bacterial and fungal infections, respiratory infections, wound healing

Usnic acid, polyphenols, mucilage

Disrupts bacterial protein synthesis, inhibits gram-positive bacteria

Respiratory infections, cold and flu, digestive infections, immune support

Andrographolide, neoandrographolide, deoxyandrographolide

Stimulates immune system, inhibits viral replication, anti-inflammatory effects